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Combining Amino Acid and Vitamin D Supplementation with Exercise Training Increases Skeletal Muscle Mass and Prevent Bone Mineral Density Loss in Participants with Low Muscle Mass
https://kmu.repo.nii.ac.jp/records/140
https://kmu.repo.nii.ac.jp/records/140c7d74802-c07a-4e3e-9b96-d13c1ad6a868
| 名前 / ファイル | ライセンス | アクション |
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論文要旨（要約） (123.1 kB)
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審査結果要旨 (98.0 kB)
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主論文 (320.7 kB)
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| Item type | 学位論文 / Thesis or Dissertation(1) | |||||
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| 公開日 | 2020-08-26 | |||||
| タイトル | ||||||
| タイトル | Combining Amino Acid and Vitamin D Supplementation with Exercise Training Increases Skeletal Muscle Mass and Prevent Bone Mineral Density Loss in Participants with Low Muscle Mass | |||||
| タイトル | ||||||
| タイトル | Combining Amino Acid and Vitamin D Supplementation with Exercise Training Increases Skeletal Muscle Mass and Prevent Bone Mineral Density Loss in Participants with Low Muscle Mass | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_46ec | |||||
| 資源タイプ | thesis | |||||
| 別タイトル | ||||||
| その他のタイトル | 筋量低下者に対するアミノ酸とビタミン D 併用運動療法は筋量を増加させ骨密 度の低下を予防する | |||||
| 著者 |
Cao Thi Thu, Ha
× Cao Thi Thu, Ha× Cao Thi Thu, Ha× Kurose, Satoshi× Fukushima, Yaeko× Takao, Nana× Nakamura, Natsuko× Kitamura, Akiko× Higurashi, Kyoko× Kamo, Tomohiro× Yoshiuchi, Sawako× Onishi, Katsuko× Tsutsumi, Hiromi× Kimura, Yutaka |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | This study evaluated the impact of exercise training with amino acid and vitamin D supplementation on muscle and bone mass in participants with low muscle volume. Twenty-nine Japanese participants (56-84 years old) were enrolled and assigned into the supplement (n=15) and non-supplement (n=14) groups. All participants underwent a 6-month exercise program. Supplements and nutrition support were provided to the participants in the supplement group for 12 weeks. Body composition and whole bone mineral density (BMD) were measured using dual energy x-ray absorptiometry. The outcomes, including body composition, whole BMD, and skeletal muscle mass index (SMI), were evaluated twice: pre- and post-intervention. The SMI was 6.51(6.28; 7.14) and 5.58 (5.24; 6.05) (kg/m2 ) in men and women, respectively. The average SMI change was 0.13% (-0.05%; 0.31%) and 2.33% (-0.88%; 5.48%); [mean (lower; upper quartile)]. The average BMD loss in the non-supplement group was -2.78%, and the BMD increased in the supplement group by 4.34%; there was an absolute difference between the two groups (p<0.05). After the intervention, serum myostatin was changed (p=0.001, non-supplement>supplement), serum vitamin D was increased (p=0.03; supplement>non-supplement), and BMD was maintained (p=0.03, supplement>non-supplement). There was a significant difference in the serum myostatin level at baseline and at 6-month in the non-supplement group, with a mean difference of 483.78 ng/ml (p=0.01). There was no significant improvement in the total lean mass, and handgrip strength. Resistance exercise combined with an amino acid supplement affects muscle and bone mass in the short-term intervention. |
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| 学位名 | ||||||
| 学位名 | 博士(医学) | |||||
| 学位授与機関 | ||||||
| 学位授与機関名 | 関西医科大学 | |||||
| 学位授与年度 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | 平成29年度 | |||||
| 学位授与年月日 | ||||||
| 学位授与年月日 | 2018-03-27 | |||||
| 学位授与番号 | ||||||
| 学位授与番号 | 課博第1018号 | |||||
| 書誌情報 |
Global Journal of Health Science en : Global Journal of Health Science 巻 10, 号 2, p. 28, 発行日 2017 |
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| DOI | ||||||
| 表示名 | 10.5539/gjhs.v10n2p28 | |||||
| URL | https://doi.org/10.5539/gjhs.v10n2p28 | |||||
