| Item type |
学位論文 / Thesis or Dissertation(1) |
| 公開日 |
2021-10-14 |
| タイトル |
|
|
タイトル |
Sevoflurane in electroconvulsive therapy: A systematic review and meta-analysis of randomised trials. |
| タイトル |
|
|
タイトル |
Sevoflurane in electroconvulsive therapy: A systematic review and meta-analysis of randomised trials. |
|
言語 |
en |
| 言語 |
|
|
言語 |
eng |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Anesthetics, Intravenous |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Electroconvulsive Therapy |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Humans |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Propofol |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Randomized Controlled Trials as Topic |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Seizures |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Sevoflurane |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_46ec |
|
資源タイプ |
thesis |
| 別タイトル |
|
|
その他のタイトル |
電気けいれん療法におけるセボフルランの使用について： ランダム化比較試験のシステマティックレビューとメタア ナリシス |
| 著者 |
青木, 宣篤
Aoki, Nobuatsu
Suwa, Taro
Kawashima, Hirotsugu
Tajika, Aran
Sunada, Naotaka
Shimizu, Toshiyuki
Murai, Toshiya
Kinoshita, Toshihiko
Takekita, Yoshiteru
|
| 抄録 |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
Sevoflurane is the most commonly used inhaled anaesthetic in electroconvulsive therapy (ECT). The objective of this study was to provide an up-to-date and comprehensive review on how the use of sevoflurane affects seizure adequacy (seizure duration and postictal suppression index [PSI]) and circulatory dynamics in ECT. We performed a meta-analysis of RCTs that investigated seizure adequacy and circulatory dynamics in patients treated with ECT using sevoflurane (sevoflurane group) and intravenous anaesthetics (non-sevoflurane group). A total of 12 RCTs (377 patients and 1339 ECT sessions) were included. Sevoflurane significantly decreased the electroencephalogram (EEG) seizure durations in comparison with intravenous anaesthetics, whereas no significant difference was observed in PSI (EEG: 9 studies, standardized mean difference (SMD) = 0.74, 95% confidence interval (CI) = -1.11 to -0.38, p = 0.0002; PSI: 4 studies, SMD = -0.06, CI -0.13 to 0.25, p = 0.59). The use of sevoflurane in ECT significantly increased heart rate (HR) compared with intravenous anaesthetics (9 studies, SMD = 0.31, CI 012-0.51, p = 0.004). In the pre-planned subgroup analysis, sevoflurane significantly reduced seizure duration compared with other types of anaesthetics, including propofol, barbiturates and ketamine. Furthermore, it was found that the risk of adverse events in ECT with sevoflurane were not significantly different from intravenous anaesthetics (6 studies, risk ratio = 1.33, CI 0.95-1.86, p = 0.09), with agitaion being the most common adverse effects. The results of our study suggest that using sevoflurane for ECT significantly reduces seizure duration, increases maximum HR and brings about no difference in the adverse event risk compared with those using intravenous anaesthetics for ECT. Therefore, there may not be compelling evidence favouring sevoflurane use for ECT, except in cases where intravenous access is difficult. |
| 学位名 |
|
|
学位名 |
博士（医学） |
| 学位授与機関 |
|
|
|
学位授与機関名 |
関西医科大学 |
| 学位授与年度 |
|
|
内容記述タイプ |
Other |
|
内容記述 |
令和3年度 |
| 学位授与年月日 |
|
|
学位授与年月日 |
2021-07-14 |
| 学位授与番号 |
|
|
学位授与番号 |
課博第1105号 |
| 書誌情報 |
Journal of psychiatric research
en : Journal of psychiatric research
巻 141,
p. 16-25,
発行日 2021
|
| DOI |
|
|
|
10.1016/j.jpsychires.2021.06.030 |
|
|
https://pubmed.ncbi.nlm.nih.gov/34171759/#:~:text=DOI%3A-,10.1016/j.jpsychires.2021.06.030,-Free%20article |
論文要旨（要約） (224.8 kB)
